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Ralph B Arlinghaus Selected Research

benzyl sulfide

4/2010A Non-ATP-Competitive Dual Inhibitor of JAK2 and BCR-ABL Kinases: Elucidation of a Novel Therapeutic Spectrum Based on Substrate Competitive Inhibition.

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Ralph B Arlinghaus Research Topics

Disease

13Neoplasms (Cancer)
01/2017 - 10/2002
9BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
05/2016 - 05/2002
8Leukemia
05/2016 - 12/2002
5Breast Neoplasms (Breast Cancer)
02/2011 - 08/2003
4Philadelphia Chromosome
01/2016 - 12/2002
3Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
05/2015 - 09/2005
3Blast Crisis (Blast Phase)
07/2012 - 10/2002
3Neoplasm Metastasis (Metastasis)
02/2011 - 08/2003
2Carcinogenesis
02/2011 - 11/2009
1Prostatic Neoplasms (Prostate Cancer)
01/2018
1Inflammation (Inflammations)
01/2017
1Adenocarcinoma
01/2017
1Hematologic Neoplasms (Hematological Malignancy)
09/2013
1Multiple Sclerosis
09/2013
1Splenomegaly
09/2013
1monosomy Chromosome 7
04/2010
1Chromosomal Instability (Chromosome Stability)
01/2004
1Urinary Bladder Neoplasms (Bladder Cancer)
01/2004
1Chromosome Aberrations (Chromosome Abnormalities)
05/2002
1Disease Progression
05/2002

Drug/Important Bio-Agent (IBA)

6Imatinib Mesylate (Gleevec)FDA Link
05/2016 - 07/2005
5Tyrosine Kinase InhibitorsIBA
01/2016 - 04/2010
4Lipocalin-2IBA
01/2017 - 11/2009
4Pharmaceutical PreparationsIBA
05/2016 - 04/2010
4Proteins (Proteins, Gene)FDA Link
01/2016 - 05/2002
3Phosphotransferases (Kinase)IBA
10/2013 - 04/2010
25- (2,4- dihydroxy- 5- isopropylphenyl)- 4- (4- morpholin- 4- ylmethylphenyl)isoxazole- 3- carboxylic acid ethylamideIBA
05/2016 - 01/2015
2Aurora Kinase AIBA
02/2012 - 01/2004
2Small Interfering RNA (siRNA)IBA
03/2008 - 04/2005
22-aminopyrimidineIBA
09/2005 - 07/2005
2nilotinibFDA Link
09/2005 - 07/2005
1Androgen Receptors (Androgen Receptor)IBA
01/2018
1ruxolitinibIBA
05/2016
1TG101209IBA
01/2016
1Cre recombinaseIBA
10/2014
1Immunologic Factors (Immunomodulators)IBA
09/2013
1Immunosuppressive Agents (Immunosuppressants)IBA
09/2013
1Fingolimod Hydrochloride (FTY720)FDA Link
09/2013
1SphingosineIBA
09/2013
1NADPH Oxidases (NAD(P)H oxidase)IBA
07/2012
1Heme Oxygenase-1IBA
07/2012
1Biomarkers (Surrogate Marker)IBA
02/2011
1Somatomedin Receptors (Somatomedin Receptor)IBA
06/2010
1Adenosine Triphosphate (ATP)IBA
04/2010
1benzyl sulfideIBA
04/2010
1AgarIBA
04/2010
1Glycoproteins (Glycoprotein)IBA
11/2009
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
11/2009
1Monoclonal AntibodiesIBA
11/2009
1CXC ChemokinesIBA
04/2009
1phenethyl isothiocyanate (PEITC)IBA
09/2006
1Reactive Oxygen Species (Oxygen Radicals)IBA
09/2006
1Janus Kinase 2IBA
07/2006
1bcr-abl Fusion ProteinsIBA
07/2006
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
04/2005
1Nuclear Localization Signals (Nuclear Localization Signal)IBA
08/2003
1Syk KinaseIBA
08/2003
1Biological ProductsIBA
08/2003
1Oncogene Proteins (Oncogene Protein)IBA
12/2002
1Tyrosine (L-Tyrosine)FDA Link
10/2002
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
10/2002
1Messenger RNA (mRNA)IBA
05/2002
1p 230 (p230)IBA
05/2002

Therapy/Procedure

6Therapeutics
05/2016 - 11/2009